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We found that in leukemic cells combination of Fludarabine at a low concentration with 1,25-dihydroxyvitamin D analog synergistically regulate expression of many innate immunity-related and differentiation-related genes, which is followed by changes in respective protein levels. We also found that in blasts from patients with myelodysplastic syndrome, 1,25-dihydroxyvitamin D analog induces myeloid differentiation. Our results […]

Our group published manuscript in prestigious Biotechnology Advances describing the concept of alternative reading of the sugar code by engineered galectins. The first author of this work is Marta Kalka. Link for the full paper: https://www.sciencedirect.com/science/article/pii/S0734975025001673?via%3Dihub